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Fluorescent slide scans were acquired with an Olympus VS200 slide scanner (Olympus) using a 20 (0.8 NA) air objective and 385/470;546/570;594/620;635/690 filter sets

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To further distinguish heterogeneous conformations observed in the datasets of CTR:Cagri/CagriBB, the authentic particles of complexes were separated into multiple clusters by 3D Classification in cryoSPARC with approximately 50100k particles for each cluster

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Alcohol and Vitamin B12 Deficiency Effects Vitamin B12 is soluble in water and is stored in the body for timely use