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Mieczkowski K, Bakiri L, Griss J, Wagner EF
RELATED STORY: Weight loss drugs to credit for drop in obesity rate
& Townes, T
This performance reflects accelerating demand for high-efficacy, multi-indication GLP-1 molecules across North America, Europe, and Asia-Pacific, driven by blockbuster drugs such as semaglutide and tirzepatide
GLP-1 signaling also antagonizes voltage-dependent K + (Kv) channels via cAMP/PKA-dependent pathway in beta cells, which prevents beta-cell repolarization by reducing Kv currents
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