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No therapeutic claims are made

Mechanistic and fibroblast data are robust, but large independent randomized trials comparing GHK-Cu head-to-head with tretinoin are lacking

GSHee may represent an effective member of a novel class of thiolester drugs that are able to prevent the ventilatory depressant effects elicited by powerful opioids such as fentanyl and their deleterious effects on gas-exchange in the lungs without compromising opioid analgesia

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