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In mice treated with amoxicillin or ciprofloxacin, depletion of Lactobacillus reuteri (Firmicutes) led to reduced brain and serum GABA, downregulation of GABA-A receptors, and diminished 5-HT and DA, neurochemical changes that coincided with anxiety- and depression-like behaviors (Bibi et al., 2025)
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Chad Walding's educational content on the NativePath brand website - attributed to him as the brand's co-founder and Doctor of Physical Therapy spokesperson - when dietary protein intake drops during significant caloric restriction, the body may draw on existing collagen-based tissue reserves for amino acids, particularly the glycine and proline needed to maintain structural functions
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