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While it is not known if the impact on blood pressure was due to the medication or the participants weight loss, the lower blood pressure measures seen with tirzepatide rivaled what is seen for many hypertension medications. The current research was a planned sub-study including 600 of the participants from the SURMOUNT-1 weight loss study to determine if there was an effect on blood pressure

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Mild burning or tingling under the tongue is normal and indicates the medication is in contact with the mucosal tissue

Most commonly, patients will present with a variety of generalized symptoms including, but not limited to, nausea/vomiting, dehydration, hypoglycemia, diarrhea and abdominal pain