Mechanistically, this redoxin directly reduces lipid hydroperoxides [180,181] , alleviates ferroptosis-induced mitophagy [182] , remodels membrane phospholipid composition [183] , or diminishes inflammatory pathways [173,176]
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In parallel, growth hormonerelated pathways are also linked to fat metabolism and body composition regulation
however, evidence is emerging that increased cellular GSSG accumulation may be of equal, if not greater, importance in regulating oxidative stress-triggered detrimental effects
Cardiovascular and neurovascular injury: Protection in heart ischemia models, eye injuries, and various CNS insults through combined vascular, antiinflammatory, and antioxidative mechanisms