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Meanwhile, trending routines like skin flooding oversimplify product chemistry, often doing more harm than good
The Phase 2 and Phase 3 trials so far have shown a safety profile broadly consistent with other GLP-1 medications: gastrointestinal side effects are common, and a new signal called dysaesthesia (an abnormal skin sensation) appears more often at higher doses
It now includes oral GLP-1 drugs, amylin combinations, dual agonists, triple agonists, long-acting platforms, and differentiated assets designed for durability, tolerability, access, or broader metabolic indications
A study on patients with HCM revealed abnormal copper accumulation, and the use of the Cu2+ selective chelator tretinoin hydrochloride was found to slow or reverse disease progression in HCM (73)