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Ivell, R., Richter, D., & Balvers, M
This pattern appears consistently across obesity medications and likely reflects the metabolic differences that accompany established diabetes
Why Tirzepatide Works Differently: The dual mechanism of tirzepatide, activating both GIP and GLP-1 receptors, appears to create unique benefits
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Eli Lilly's NDA submission is expected Q4 2026 to Q1 2027, with potential FDA approval in late 2027 to 2028
