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Here's what we'll cover Here's what we'll cover Here's what we'll cover Key takeaways Tirzepatide is the active ingredient in Mounjaro and Zepbound, two injectable medications that are prescribed for weight loss, type 2 diabetes, and obstructive sleep apnea

The key difference lies in duration, intensity, and physical symptoms

In addition, aldosterone, released upon the action of angiotensin II and sympathetic nervous system hyperactivation, reduces insulin sensitivity in several cell types triggering maladaptive responses in type 2 diabetes, hypertension, and HF ( 2.2 Cognitive impairment Cognitive impairment is generally referred to Alzheimers disease and vascular dementia, recognized as the two most prevalent causes of dementia that affects about 50 million people worldwide, with cases projected to triple by 2050 (GBD, 2016 Dementia Collaborators, 2019

It recommended semaglutide be considered for weight loss in people with established cardiovascular disease, like a history of heart attacks, to reduce future risk

Emerging alternatives that may change duration considerations The GLP-1 agonist space is evolving rapidly