Semaglutide is available as both tablets and injections, while tirzepatide is only available as an injection
Dark yellow urine suggests inadequate hydration
GLP-1 receptor agonists work by: Stimulating insulin secretion from pancreatic beta cells in a glucose-dependent manner, which helps regulate blood sugar levels Slowing gastric emptying , meaning food remains in the stomach longer, promoting feelings of fullness Acting on appetite centres in the brain , particularly the hypothalamus, to reduce hunger signals and food cravings Decreasing glucagon secretion , which helps prevent excessive glucose production by the liver Most GLP-1 agonists are administered via subcutaneous injection, typically once weekly or once daily depending on the specific formulation, though oral semaglutide (Rybelsus) is also available
Semaglutide injections are placed under the skin and in the fatty tissue
Deng YQ, Xu GG, Duan P, Zhang Q, Wang JZ