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Additionally, oxidative stress and ROS can originate from xenobiotic bioactivation by prostaglandin H synthase (PHS) and lipoxygenases (LPOs) or microsomal P450s which can oxidize xenobiotics to free radical intermediates that react directly or indirectly with oxygen to produce ROS and oxidative stress [26] as in Fig (2)
Glutathione is widely used in Costa Rica for its potential to support a brighter, more even-looking skin tone
Heppner et al., 2010)
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