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A computational ONIOM model for the description of the H-bond interactions between NU2058 analogues and CDK2 active site

The pivotal clinical trials that led to FDA approvalincluding the SUSTAIN trials for diabetes management and the STEP trials for weight managementdid not identify dry mouth as a statistically significant adverse event occurring at notably higher rates in semaglutide-treated patients compared to placebo groups

Oncotarget 7 , 38323846 (2016)

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