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Under oxidative stress, excessive ROS such as OH directly attack DNA, causing single-strand or double-strand breaks, activating PARP-1, consuming NAD and ATP, and generating poly(ADP-ribose), resulting in mitochondrial membrane potential loss and the release of apoptosis-inducing factor, ultimately resulting in cell death [252]
If this occurs after you take vitamin B12, call 911 or your local emergency services immediately
People with diabetes, muscular degeneration, or Lou Gehrigs disease
you must support it with diet and exercise
Horvath K, Perman JA
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