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formulary deletions for Commercial and Healthcare Reform coverage to ensure cost-effective, clinically appropriate treatments

We plotted the continuous change in expression of and cell identity markers ARX, DNA methyltransferase 1 (DNMT1 ), MAFA , and PDX1 in the and cell subclusters (Figure 3E)

doi: 10.1016/j.cell.2014.10.029 146 EganBZierathJR

These divergent effects on ARE-bindings were reflected in the expression of AR-dependent genes that were impacted by SUMOylation: genes activated by AR negatively regulate cell proliferation, and those repressed by AR are involved in pattern formation by WNT, TGF-B, and FGF signaling [74]

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