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A 2020 meta-analysis of 37 randomized controlled trials with over 2,200 participants found that L-carnitine supplementation led to an average weight loss of 1.21 kg, a slight drop in BMI, and a reduction in fat mass by about 2.08 kg, especially in people with overweight or obesity

Admittedly, these metabolic analyses were focused on the initial phase of treatments, as this period displayed the largest changes in body weight and is less likely affected by compensatory responses, which might confound the identification of primary mechanisms

However, it is not clearly known how much of these ingredients actually pass through the skin and reach the bloodstream to produce noticeable effects

Kapoor, M

GSH levels were also evaluated among different age groups of the study participants, and the results are shown in Figure 3