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Regarding altered neuronal/synaptic activity, a reduced glutamatergic projection from ACC to the ventral hippocampal CA1 area is suggested to contribute to depressive-like symptoms in 3-month-old 5xFAD mice (Chen et al., 2024)

In these populations, IV or injectable B12 can swiftly correct deficiencies and reverse related complications such as peripheral neuropathy, cognitive decline, and megaloblastic anemia

However, pregnant women, individuals with specific health conditions, or those on certain medications should consult a medical professional before proceeding

Mitochondrial redox signaling and oxidative stress in kidney diseases