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Dose response relationships Tirzepatide demonstrates clear dose dependent efficacy for weight loss
Semaglutide (Ozempic/Wegovy): a GLP-1 receptor agonist that reduces appetite and slows gastric emptying, which is part of why weight loss can be substantial
DOI: 10.1056/NEJMoa2301972 Tirzepatide Once Weekly for the Treatment of Obesity New England Journal of Medicine, 2022
Semaglutide at 2.4 milligrams (the dose used for weight loss) achieves a 1517% reduction in body weight
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