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Researchers do not know all its potential side effects or drug interactions
Efflux into the urine is mediated by the transporter ABCG2 (Takada et al., 2018)
There are also less common but important risks including gallbladder disease, pancreatitis, dehydration from vomiting or diarrhea, worsening reflux or gastroparesis symptoms
Hormonal fluctuations, particularly the menstrual cycle in women, can cause regular monthly water retention patterns that completely obscure fat loss for one to two weeks per cycle
They should be administered by trained clinicians who screen properly first
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