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*Correspondence: Yi Hua, [email protected] This article was submitted to Experimental Pharmacology and Drug Discovery, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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Recently, hypoxia-induced expression of the SLC1A5 variant was shown to be mediated by HIF-2 and to lead to metabolic reprogramming toward glutamine metabolism in pancreatic cancer cells 16