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Major plasma collection organizationsincluding CSL Plasma, BioLife Plasma Services, and Grifolsmaintain internal medication policies that supplement FDA regulations
Long term administration of agonists could potentially lead to unanticipated consequences in these organs
According to FDA prescribing information, these include: Nausea (occurring in 1544% of patients depending on the specific agent and dose) Vomiting (524% of patients) Diarrhea (821% of patients) Constipation (1024% of patients) Abdominal pain or discomfort (514% of patients) These symptoms typically emerge during dose initiation or escalation and often diminish over several weeks as the body adapts
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