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Abeywickarama B, Ralapanawa U, Chandrajith R (2016) Geoenvironmental factors related to high incidence of human urinary calculi (kidney stones) in central highlands of Sri Lanka

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Since then, it has been dramatically used, especially following its approval for weight loss and its demonstrated efficacy in reducing cardiovascular risks and kidney protective mechanisms in diabetic patients

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One patient presented with bilateral papillitis, a rare inflammation of the optic nerve, while another suffered from paracentral acute middle maculopathy, which is marked by impaired blood flow to the retina, potentially affecting central vision