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Cancer Risk Elevated levels of insulin-like growth factor-1 (IGF-1), which is the downstream effect of GH activity, have also raised theoretical concerns about an increased risk of cancer: According to Roberts, IGF-1 promotes cellular proliferation and inhibits apoptosis, two mechanisms that may contribute to the development of cancer cells in predisposed individuals (22)
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Escalation decisions should rely on objective data rather than subjective tolerance alone
doi: 10.3389/fphar.2023.1142127 24 TabbalHSeptierAMathieuMDrelonCRodriguezSDjariCet al
DPSCs were extracted from fresh, caries-free, pulpitis-free, and non-necrotic third molars or from intact permanent teeth extracted for orthodontic purposes
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