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We next examined immunovascular interactions in PBMCs isolated from patients with COVID-19 and found increased adhesion of PBMCs to human brain endothelial cells in the cohort with long COVID compared to unaffected individuals, which was heightened in the presence of TNF and only modestly affected by blocking antibodies against ICAM-1 and VCAM-1 (Extended Data Fig
This, in turn, can result in B12 deficiency
Many patients see modest, gradual weight changes, but the focus is balance and consistency rather than rapid loss
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