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In the study by Lee et al , 4 biallelic inactivation of SUZ12 or EED was identified in 69% (34/49) of malignant peripheral nerve sheath tumors (epithelioid variant excluded), which is in accordance with the rate of H3K27me3 complete loss (72%) observed in our study

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Patients in these states need to use alternative compounding pharmacies

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doi: 10.1038/ng.2901 47

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