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Description

Gclc , forward 5-GATTCAGGCTCCGGGCTATG-3, reverse 5-TGGGTCTCTTCCCAGCTCAGT-3

Miller H et al

GLP-1 drugs tend to delay gastric emptying and intestinal motility , which might reduce diarrhoea frequency and urgency

Among these, compounds 53 (IC 50 = 4 nM) and 54 (IC 50 = 10 nM) exhibited high DPP-4 inhibitory activities, good efficacy, and selectivity in an oral glucose tolerance test in ICR mice (Figure 7)