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However, broader guidance from NICE, the NHS, and the MHRA provides a clear framework for understanding how unapproved substances should be approached

This just means the unsaturated fatty acids are turned into saturated ones so they don't go bad as easily

An elevated resting heart rate can increase long-term cardiovascular risk, and regulators need robust data confirming that the metabolic benefits outweigh this potential downside

Timeline and Expectations Understanding realistic timelines helps set appropriate expectations and prevents premature discontinuation before therapeutic effects fully develop

Some early studies in animals have shown a potential risk to foetal development, which is why current advice is to avoid use in pregnancy and stop treatment well in advance of trying to conceive