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virology 58 (1), 100104

Upon activation, the influx of cations mediated by Piezo1, primarily Na + and Ca 2+ , leads to membrane depolarization, effectively transforming mechanical stimuli into electrochemical responses[36, 37]

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We selected these trials due to their similarities in assessing patients with both obesity and T2D, treatment duration, clinical development phase (phase 3), and use of semaglutide as an active treatment arm

This discovery enabled development of medications targeting desire at its source in the brain, representing a fundamentally different approach from peripheral vasodilators