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Common symptoms of psoriasis include: Mild to severe itching, burning, or soreness Red patches of skin covered with thick, silvery scales Dry, cracked skin that might bleed Small scaling spots which are frequently teardrop shaped and most often seen in children Thickened, pitted or ridged nails, which could indicate skin buildup underneath Swollen and stiff joints, in addition to any of the above While not a symptom per say, arthritis is a common consequence of psoriasis

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Evidence suggests that REE particles may persistently accumulate in lung tissue, dysregulate multiple signaling pathways, and may contribute to structural and functional impairment of the respiratory system (134), while immobilization on SiO surfaces may confer anti-inflammatory and antioxidant effects (135)

One key component of atherosclerosis is vascular smooth muscle proliferation, previous studies have demonstrated the effects of GLP-1 agonists in reducing vascular remodeling in murine models

These improvements occur because weight loss reduces liver fat content and improves insulin sensitivity, both of which are driving factors in cholesterol production