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Abstract Glucagon-like peptide-1 receptor agonists (GLP-1RAs)along with the dual glucose-dependent insulinotropic polypeptide (GIP)/GLP-1RA tirzepatideare widely acknowledged for their efficacy in managing both type 2 diabetes mellitus and obesity, with expanding indications in cardiometabolic risk reduction

9% of Britons and 10% of Americans experienced reduced PMS symptoms, such as mood swings and bloating

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Reduced glucose-lowering effect: corticosteroids, diuretics, oestrogens, progestogens