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Together, excessive and reduced production of neuro-toxic and -protective kynurenines, respectively, may exacerbate excitotoxicity and neuroinflammation, establishing a feed-forward cycle of KP dysregulation, 5-HT depletion, HPA axis hyperactivity, and increased vulnerability to MDD

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Intracellular and extracellular redox status and free radical generation in primary immune cells from children with autism

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