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In addition to the disruption in iron homeostasis, nuclear receptor coactivator 4-mediated ferritinophagy can lead to iron accumulation and ferroptosis [24]

Studies have suggested that some dietary compounds, such as resveratrol (Zhao et al., 2019), grape pomace (Liu et al., 2018), lactofermented Annurca apple puree (Tenore et al., 2019) and Oolong tea extract (P

Therefore the in vivo effect of oral supplementation with Gln and GSH was assessed

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Select heterozygous Keap1 mutations have a dominant-negative effect on wild-type Keap1 in vivo