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Acknowledgement The authors would like to thank the UK Biobank for approving our application (#42468)
Lifestyle changes What happens when you have changed your diet while taking a GLP medication to nutrient-dense food items and still your weight loss begins to stagnate
Effects of once-weekly subcutaneous retatrutide on weight and metabolic markers: A systematic review and meta-analysis of randomized controlled trials
Aim for 1.21.6 g of protein per kg of goal body weight daily while on GLP-1 medications Muscle loss during weight loss can lower metabolic rate and increase regain risk The protein-first strategy ensures you prioritize protein even with reduced appetite Resistance training 23 times per week is essential for preserving lean mass GI side effects can make protein challenging cold foods and smaller meals help Why protein matters more on GLP-1 medications GLP-1 medications like Wegovy and Zepbound reduce appetite significantly, which is how they help you lose weight
Dehydration can also worsen common tirzepatide side effects like constipation, which may indirectly affect appetite regulation
