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Tirzepatide FDA-approved as Mounjaro for type 2 diabetes (2022) and Zepbound for obesity (2023)
The new phase of high-quality weight loss: healthy slimming Currently, the weight-loss drug market is dominated by GLP-1-based therapies, which can achieve 2025% body weight reduction within a year and continue to push the limits of achievable weight loss
The extremely long half-life (~12 days) raises additional concerns about compound accumulation with chronic daily dosing
Bottom line: Cagrilintide is a promising but investigational drug, currently restricted to clinical research settings
It is also a required substrate for sirtuins and PARP enzymes involved in DNA repair, gene regulation and processes tied to aging [5] [6]
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