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Obesity creates inflammatory environment and mechanical stress
Mol Cell Biochem 303:4551 Dasuri K, Zhang L, Keller JN (2013) Oxidative stress, neurodegeneration, and the balance of protein degradation and protein synthesis
Thrombomodulin is a receptor that binds to thrombin and inactivates it
However, this is rarely necessary outside of research
The peptide is also unusually stable in stomach acid for a peptide, so an oral capsule format exists and is sometimes used in gut-focused research planning
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