Patients transitioning from semaglutide should understand the conversion considerations involved, as the two medications are not directly interchangeable at the same milligram doses
Interaction of SARS-CoV-2 proteins with specific host cellular targets could rewire sugar-, AA-, FA-, as well as nucleotide-metabolism(s), and distinctly alter or impair bioenergetics, immune response, and redox homeostasis in the human body, thereby facilitate viral life cycle 21,22
doi: 10.1056/NEJMe2202547 123 IottiS.WolfF.MazurA.MaierJ
In fact, native GLP-1 (7-36 amide) has a plasma half-life of ~12 minutes IV, and only ~5 minutes when subcutaneously injected ( [39] )
You may also want to reduce portion sizes and limit fat, sugar, and processed foods to cut calories