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Mantovani A, Byrne CD, Benfari G, Bonapace S, Simon TG, Targher G
This Article at a Glance: GLP-1 Therapies: Effective for weight loss (up to 15% body weight), enhanced insulin sensitivity, and cardiovascular health improvements
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The effects of DPP-4 on bone health are underscored by its effects in generating proinflammatory cytokines such as interleukin-6 (IL-6) and tumor necrosis factor-alpha (TNF-), contributing to inflammatory processes mediated by adipose tissue macrophages, which are implicated in conditions ranging from obesity to osteoporosis [21]
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