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Prolonged release melatonin in the treatment of primary insomnia: evaluation of efficacy and safety in older adults

Participants are able to join and complete study activities from home or locally, without having to travel to a specific study site or location

8 This effect increased with duration of therapy, and patients had an unclear prophylactic supplementation response

Thermal equilibration was then conducted for 20 ps, gradually increasing the temperature from 100 K to 298 K using the Langevin thermostat (collision frequency of 1 ps 1 )

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