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Laboratory Research Only For research purposes only
Sensitivity analyses showed consistent results, including restricting outcomes to inpatient visits, conducting an intention-to-treat analysis, applying a prevalent new user design, and substituting SGLT2 inhibitors with dipeptidyl peptidase-4 (DPP4) inhibitors as the active comparator
Animal reproduction studies have shown adverse effects on fetal development at high doses, though animal data doesn't always predict human outcomes
Safety Profile PEG-MGF (pegylated mechano growth factor) demonstrates good tolerability in preclinical studies with minimal immunogenicity from pegylation modifications