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Clinical trial data recorded headache as the most frequent adverse event, occurring in a small percentage of participants

Inflammation-triggered self-immolative conjugates enable oral peptide delivery by overcoming gastrointestinal barriers

She had a brother who died at the age of 38 years due to a jejunal perforation followed by a second perforation of the sigmoid colon three days later

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First, a bacterial reverse mutation test (Ames test) assessed AOD9604s mutagenic potential using four histidine-dependent auxotrophic mutants of Salmonella typhimurium (TA1535, TA1537, TA98, TA100) and one tryptophan-dependent auxotrophic mutant of Escherichia coli (WP2 uvrA), using both plate incorporation and pre-incubation methods at doses of 0, 1.6, 8, 40, 200, 1,000, and 2,000 g AOD9604/plate