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These rare allergic reactions can include itching or rash, fever, swollen tongue, and other symptoms (Vassavada, 2021

Other growth factors such as bone morphogenetic proteins (BMPs) have received FDA approval for specific indications and may represent more appropriate therapeutic choices for conditions where approved therapies are available and indicated

Endocrine disorders, including hypothyroidism and adrenal insufficiency, were considered owing to fatigue, depression, and musculoskeletal pain

Maintenance Phase: Many users transition to maintenance dosing during this period, having achieved significant metabolic improvements

and (2) binding antibodies bind to the "cobalamin-intrinsic factor" complex and prevent its absorption at the terminal ileum