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The 2021 Akar paper in Journal of Obstetrics and Gynaecology documented anti-proliferative activity of small-molecule NNMT inhibitors in HeLa cell systems (PMID 33645410)

This was because the drug did not significantly reduce weight in 536 subjects over the course of 24 weeks 2

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Throw away any unused medication after the expiration date

The dosing frequency guide discusses the tradeoffs in detail