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The Achieve-3 trial, funded by Eli Lilly, studied more than 1,500 adults with type 2 diabetes from 131 medical research centres and hospitals in Argentina, China, Japan, Mexico and the US

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By inhibiting NNMT, the body maintains higher NAD levels, which in turn activate SIRT1, a longevity-associated gene, which may improve mitochondrial activity, fat oxidation, insulin sensitivity, and by overall energy balance

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Insulin resistance makes it harder for your body to utilize glucose (blood sugar) as a source of energy, leading to weight gain and increasing the risk of diabetes