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Since semaglutide slows gastric emptying, there is a theoretical risk of altered absorption rates for oral medications

In many cases, these shifts are closely tied to weight regain rather than the medication itself

In addition, patients can be trialed on L-carnitine (50-100mg/kg/day divided TID to max 1g TID) and CoezymeQ10 (10mg/kg/day divided TID to max 100mg TID), both of which may reduce the frequency and severity of symptoms, though data is not high quality [6]

Dysbiosis in the gut, particularly reduced microbial diversity, correlates with increased eczema severity in both children and adults

These effects create synergistic benefits that exceed what would be expected from simple addition of single-pathway therapies