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Dextran sodium sulfate (DSS) colitis was induced in 8-week-old co-housed WT and Gpx4 +/IEC mice using 3% DSS (MP Biomedicals, 02160110) given in drinking water ad libitum for five consecutive days followed by tap water for the rest of the experiment

However, when looking to combine therapies, its essential for a medical professional to review labs and develop a customized treatment plan ahead of time to avoid unnecessary risks

Structural mechanisms for regulation of GSDMB pore-forming activity

The kidneys are also critical in metabolic and energy regulation through their ability to contribute to endogenous glucose production via gluconeogenesis

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