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Brands looking to serve these individuals better should identify ways they can supplement their needs both pre- and post-GLP-1 usage, especially weight loss users whose time on the drug will likely be limited

However, in contrast, a 2020 analysis that looked at berberine studies found essentially no significant weight loss effect at all (just 0.25 pounds on averageabout the weight of a small apple)

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In a maintenance trial, nausea affected 47% of participants during escalation but fell to 14% after the same 2.4 mg dose was held. Receptor exposure stayed constant