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Effects of cerebral glucose levels in infarct areas on stroke injury mediated by blood glucose changes

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Cells have developed a sophisticated antioxidant system to protect against these oxidative insults, consisting of enzymes that either convert superoxide radicals into hydrogen peroxide (H 2 O 2 , SOD1, and catalases) or H 2 O 2 into water and oxygen [peroxiredoxin (Prx) and glutathione peroxidase (GPx)

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We interpret this result as being due to pyocyanin-mediated decline in GRed activity that manifests as insufficient enzymatic activity for the conversion of exogenously added GSSG to GSH

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