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SKU: 38392963776

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161 (4): 13251332.e7

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In line with NICE guidance (e.g., NG28 for type 2 diabetes

The first reaction (indicated by 1 in the Figure below) of purine synthesis is catalyzed by an enzyme called glutamine phosphoribosylpyrophosphate amidotransferase that is encoded by the PPAT gene (phosphoribosylpyrophosphate amidotransferase: PRPP amidotransferase)