incretin semaglutide Targeting the system in obesity and type 2 diabetes mellitus GLP-1s like semaglutide are not

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doi: 10.1002/jimd.12060 19 Abou-SalehMTCoppenA

PEPTIDE SEQUENCE H-Aib-Glu-Gly-Thr-Phe-Thr-Ser-Asp-Val-Ser-Ser-Tyr-Leu-Glu-Gln-Lys-Ala-Ala-Gln-Ala-Ala-Lys-Glu-Phe-Ile-Ala-Trp-Leu-Val-Arg-Gly-Arg-NH

Administration of CK to C6 rat glioma cells reduced stromal cell-derived growth factor 1 (SDF-1) induced invasion and migration, characterised by the decreased expression of matrix metallopeptidase (MMP)9, MMP2, p-protein kinase C alpha (PKC) and p-extracellular-signal-regulated kinase (ERK)1/2 [254]