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These microbial changes correlate with higher lipopolysaccharide (LPS) and lower superoxide dismutase-1 levels (59, 60), which can lead to microbial translocation, systemic inflammation, and increased permeability of both the intestinal and blood-brain barriers (BBB), creating a vicious cycle (6165)

Mrek, T., Drahota, Z

Their clinical value lies in enabling disease monitoring, guiding therapeutic adaptation, prevention of relapses, and improving medium and long-term prognosis

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