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Retatrutide appears to have a similar safety profile to other GLP-1 medications: No increased risk of pancreatitis in trials so far No hepatotoxicity signals (liver damage) No cases of ketoacidosis Serious adverse events were rare (2.5% of participants) The trials are ongoing, so we'll learn more about long-term safety
PMID 25038357
Compounded semaglutide treatments, which are not FDA-approved, are advertised as semaglutide mixed with other ingredients or additives
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